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Importantly, BV8s involvement in MDSC-driven angiogenesis and immune suppression has highlighted it as a significant checkpoint in the immunosuppressive landscape of various cancers, including thoracic and colorectal malignancies [107]
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Abstract Uncontrolled oxidative stress, reported in Salmonella and HIV infections, colorectal cancer or severe acute malnutrition, has been associated with anaerobic gut microbiome alteration, impaired butyrate production, mucosal immunity dysregulation and disruption of host-bacterial mutualism